Advancing Stroke Recovery Through Improved Articulation of Nonpharmacological Intervention Dose

KS Hayward; L Churilov; EJ Dalton; A Brodtmann; BCV Campbell; D Copland; N Dancause; E Godecke; TC Hoffmann; NA Lannin; MW Mcdonald; D Corbett; J Bernhardt

Journal article

Advancing Stroke Recovery Through Improved Articulation of Nonpharmacological Intervention Dose

KS Hayward, L Churilov, EJ Dalton, A Brodtmann, BCV Campbell, D Copland, N Dancause, E Godecke, TC Hoffmann, NA Lannin, MW Mcdonald, D Corbett, J Bernhardt

Stroke | LIPPINCOTT WILLIAMS & WILKINS | Published : 2021

DOI: 10.1161/STROKEAHA.120.032496

Abstract

Dose articulation is a universal issue of intervention development and testing. In stroke recovery, dose of a nonpharmaceutical intervention appears to influence outcome but is often poorly reported. The challenges of articulating dose in nonpharmacological stroke recovery research include: (1) the absence of specific internationally agreed dose reporting guidelines; (2) inadequate conceptualization of dose, which is multidimensional; and (3) unclear and inconsistent terminology that incorporates the multiple dose dimensions. To address these challenges, we need a well-conceptualized and consistent approach to dose articulation that can be applied across stroke recovery domains to stimulate ..

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University of Melbourne Researchers

Kate Hayward Author

Leonid Churilov Author

Emily Dalton Author

Amy Brodtmann Author

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Grants

Awarded by Canadian Institutes of Health Research

Funding Acknowledgements

Person: National Health and Medical Research Council (NHMRC): Dr Hayward, No. 1088449; Dr Bernhardt, No. 1154904; Dr Campbell, No. 1174514. National Heart Foundation of Australia: Dr Lannin, FLF102055; Dr Brodtmann, FLF100784. Fonds de Recherche du Quebec-Sante (389886): Dr Dancause. Research Training Program Scholarship: E. J. Dalton. Canadian Vascular Network: Dr McDonald. Project: NHMRC Centre of Research Excellence in Stroke Rehabilitation and Brain Recovery: Dr Bernhardt/Dr Churilov (No. 1077898). NHMRC Centre of Research Excellence in Aphasia Recovery and Rehabilitation: Dr Copland/Dr Godecke/Dr Bernhardt/Dr Churilov. NHMRC grant (No. 1044973): Dr Godecke. Canadian Institutes of Health Research grant (No. 389886): Dr Dancause. Canadian Partnership for Stroke Recovery grant: Dr Hayward/Dr Corbett/Dr McDonald/Dr Churilov/E.J. Dalton.